Heath Ledger
Heath was a rising superstar who gave The Dark Knight its fame for his role as the Joker. He died before the movie was released due to an accidental overdose of prescription drugs. He did win a posthumous Oscar for Best Supporting Actor, though!
Brittany Murphy
She enjoyed her days as the Clueless star that had a rising career ahead of her. However, she died at a very young age from complications of pneumonia and anemia.