Tramadol (Ultram)
Tramadol (Ultram) is a narcotic-like prescription pain drug which acts like both an opioid pain reliever and an antidepressant and can help ease short-term pain in lupus patients. Like opioids, this drug is addictive and should be taken with extreme caution and supervision from a doctor. Some of its side effects include the following: constipation, nausea, dizziness, vertigo, vomiting.