3. St. Louis, Missouri

One of two Missouri cities appearing on this list, the other being Springfield, St. Louis ranks third worst city to live in in the United states. Violence in parts certain parts of the city makes it very dangerous for residents and affects their overall quality of life. It has the third highest crime rate among other US cities, with almost 2,000 violent crimes for every 100,000 people recorded. This has been one of the major reasons for the Missouri city losing more residents over the past 10 years, its population decreasing by as much as 11.2% despite a national average up-tick of 7.1%