6. Painful Muscle Spasms

One of the more common signs of Multiple Sclerosis is muscle spasticity, which can either be described as a mild tightening of muscles, or as a severe cramping and tightening of the arms, back, and legs, with the latter of the 3 a much more common complaint. This tightening of the muscles, especially around the joints, are often painful and debilitating for patients, preventing them from functioning normally.